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SOUTH AFRICAN HEALTH PRODUCTS REGULATORY AUTHORITY (SAHPRA) 
 
The South African Health Products Regulatory Authority (SAHPRA) is the National Medicines Regulatory Authority established in terms of the Medicines and Related Substances Act, 101 of 1965, as amended, to provide for the monitoring, evaluation, regulation, investigation, inspection, registration and control of medicines, scheduled substances, clinical trials and medical devices, and related matters in the public interest.
 


​MANAGER: ICT

SALARY: R1 565 650  R 1 661 741 PER ANNUM (TOTAL COST TO COMPANY)
Ref No.: SAHPRA 60 of 2025/26
CENTRE: Pretoria
 
REQUIREMENTS: ● Applicants must have a Matric certificate and an appropriate four-year Bachelors degree or equivalent NQF level 7 as recognised by the South African Qualifications Authority (SAQA) in Computer Science or an Information Technology related qualification.
Certification: COBIT 2019 Foundation, COBIT 2019 Design and Implementation certifications, ITIL Foundation and/or Practitioner certificate, CISSP (Certified Information Systems Security professional) or CISM (Certified Information Security Manager)
 
Other requirements: PMP (Project Management Professional) or PRINCE2 Practitioner, Cloud architecture certifications (AWS Solutions Architect, Azure Solutions Architect), AI/ML certifications (Microsoft AI Engineer, Google Cloud ML Engineer), Privacy certifications (CIPP/E, CIPM)
 
EXPERIENCE: Minimum of five (5) years progressive ICT management experience with a minimum of three years in senior leadership roles. ● Demonstrated experience in cybersecurity management and digital transformation leadership. ●Experience with AI/ML implementation and emerging technology adoption. ●Proven track record in regulatory compliance and governance (preferably pharmaceutical/healthcare)
 
COMPETENCIES, KNOWLEDGE AND SKILLS: *ICT Unit business leader & ICT Team leadership capabilities, *Advanced cybersecurity expertise including zero-trust architecture, SIEM/SOAR platforms, *AI/ML technologies, natural language processing, and intelligent automation, *Digital transformation methodologies and change management, *Digital transformation methodologies and change management, *Cloud computing architectures (hybrid, multi-cloud strategies), *Enterprise architecture frameworks (TOGAF, Zachman), *DevSecOps practices and infrastructure as code, *Solid Stakeholder management skills, *Solid Vendor management skills, *Effective Communication Skills, *Solid Leadership and Management Skills, *Performance measurement skills, *Performance measurement skills, *Problem-solving skills, *Budget Management skills, *ICT Unit business leader & ICT Team leadership capabilities,
 
DUTIES: 
Strategic Planning & Technology Leadership: Develop, secure approval, and implement strategic technology plans aligned with business goals and digital transformation objectives. Define and maintain enterprise architecture frameworks (e.g., TOGAF, Zachman) and technology roadmaps. Lead cloud migration strategies and implement Infrastructure as Code (IaC) solutions.
 
Infrastructure & Application Management: Oversee IT infrastructure components, including servers, networks, storage systems, databases, and virtualization technologies. Ensure scalability, resilience, and security-by-design across all IT resources. Manage enterprise applications portfolio (ERP, CRM, regulatory systems), ensuring high availability (99.5%+) and optimal performance. Drive application lifecycle management, modernization initiatives, and cloud-first hosting strategies. Implement robust application security standards and manage integrations via API platforms.
 
Cybersecurity & Risk Management: Develop and execute cybersecurity strategies aligned with ISO 27001 and NIST frameworks. Establish governance structures, incident response teams, and zero-trust architecture principles. Conduct regular risk assessments, vulnerability management, and penetration testing. Maintain security awareness programs with 95%+ staff completion and report KPIs quarterly. Develop and test business continuity and disaster recovery plans with defined RPO/RTO targets.
 
AI Strategy & Implementation: Define organisational AI strategy and governance aligned with business objectives. Evaluate, pilot, and implement AI tools for operational efficiency and compliance. Establish ethical AI practices and risk management frameworks addressing bias, privacy, and regulatory concerns. Lead AI projects with measurable ROI and create staff competency development programs.
 
Data Management & ICT Governance: Implement ICT governance frameworks (COBIT 2019, KING IV), ensuring compliance with POPIA, GDPR, and pharmaceutical regulations (GxP). Establish data governance standards, classification, and protection measures. Maintain audit readiness and manage vendor governance and third-party risk programs. Ensure timely preparation and submission of governance, strategic, and operational reports.
 
Digital Transformation Oversight: Lead enterprise digital transformation initiatives aligned with organizational strategy. Manage ICT transformation projects using PMI or PRINCE2 methodologies. Drive automation, cloud migration, and digital workplace technologies. Oversee change management programs and ensure measurable business value delivery.
 
Team Leadership & Project Management: Manage and develop IT teams, assign tasks, and conduct annual performance reviews. Lead IT projects from initiation to completion, ensuring delivery within scope, time, and budget. Foster team capabilities in emerging technologies, cybersecurity, and digital transformation.
 
Budgeting, Procurement & Vendor Management: Prepare and manage annual IT budgets (CAPEX/OPEX) and monitor monthly expenses. Evaluate and select technology vendors, negotiate contracts, and manage service agreements. Ensure vendor solutions meet strategic objectives and compliance requirements.
 
Technology Evaluation & Implementation: Assess emerging technologies (AI, automation, cybersecurity) for organizational impact. Secure stakeholder alignment and oversee successful change management during implementation.





​INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):

 Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources
 Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.
 Incomplete applications or applications without the aforementioned documents or information will not be considered.
 No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
 Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
 Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
 Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
 SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
 SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
 SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
 SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013.
CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
 Applications should be submitted through the SAHPRA Website Online Portal: https://www.sahpra.org.za/vacancies.
 For enquiries: Please contact Mr I Mosenyi, HR Business Partner, via email at itumeleng.mosenyi@sahpra.org.za. NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
 The closing date is 12 February 2026 at 16:00.