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SOUTH AFRICAN HEALTH PRODUCTS REGULATORY AUTHORITY (SAHPRA) VACANCIES
SOUTH AFRICAN HEALTH PRODUCTS REGULATORY AUTHORITY (SAHPRA)
The South African Health Products Regulatory Authority (SAHPRA) is the National Medicines Regulatory Authority established in terms of the Medicines and Related Substances Act, 101 of 1965, as amended, to provide for the monitoring, evaluation, regulation, investigation, inspection, registration and control of medicines, scheduled substances, clinical trials and medical devices, and related matters in the public interest.
MANAGER: ICT
SALARY: R1 565 650 – R 1 661 741 PER ANNUM (TOTAL COST TO COMPANY)
Ref No.: SAHPRA 60 of 2025/26
CENTRE: Pretoria
REQUIREMENTS: ● Applicants must have a Matric certificate and an appropriate four-year Bachelors degree or equivalent NQF level 7 as recognised by the South African Qualifications Authority (SAQA) in Computer Science or an Information Technology related qualification.
Certification: COBIT 2019 Foundation, COBIT 2019 Design and Implementation certifications, ITIL Foundation and/or Practitioner certificate, CISSP (Certified Information Systems Security professional) or CISM (Certified Information Security Manager)
Other requirements: PMP (Project Management Professional) or PRINCE2 Practitioner, Cloud architecture certifications (AWS Solutions Architect, Azure Solutions Architect), AI/ML certifications (Microsoft AI Engineer, Google Cloud ML Engineer), Privacy certifications (CIPP/E, CIPM)
EXPERIENCE: Minimum of five (5) years progressive ICT management experience with a minimum of three years in senior leadership roles. ● Demonstrated experience in cybersecurity management and digital transformation leadership. ●Experience with AI/ML implementation and emerging technology adoption. ●Proven track record in regulatory compliance and governance (preferably pharmaceutical/healthcare)
COMPETENCIES, KNOWLEDGE AND SKILLS: *ICT Unit business leader & ICT Team leadership capabilities, *Advanced cybersecurity expertise including zero-trust architecture, SIEM/SOAR platforms, *AI/ML technologies, natural language processing, and intelligent automation, *Digital transformation methodologies and change management, *Digital transformation methodologies and change management, *Cloud computing architectures (hybrid, multi-cloud strategies), *Enterprise architecture frameworks (TOGAF, Zachman), *DevSecOps practices and infrastructure as code, *Solid Stakeholder management skills, *Solid Vendor management skills, *Effective Communication Skills, *Solid Leadership and Management Skills, *Performance measurement skills, *Performance measurement skills, *Problem-solving skills, *Budget Management skills, *ICT Unit business leader & ICT Team leadership capabilities,
DUTIES: Strategic Planning & Technology Leadership: Develop, secure approval, and implement strategic technology plans aligned with business goals and digital transformation objectives. Define and maintain enterprise architecture frameworks (e.g., TOGAF, Zachman) and technology roadmaps. Lead cloud migration strategies and implement Infrastructure as Code (IaC) solutions. Infrastructure & Application Management: Oversee IT infrastructure components, including servers, networks, storage systems, databases, and virtualization technologies. Ensure scalability, resilience, and security-by-design across all IT resources. Manage enterprise applications portfolio (ERP, CRM, regulatory systems), ensuring high availability (99.5%+) and optimal performance. Drive application lifecycle management, modernization initiatives, and cloud-first hosting strategies. Implement robust application security standards and manage integrations via API platforms. Cybersecurity & Risk Management: Develop and execute cybersecurity strategies aligned with ISO 27001 and NIST frameworks. Establish governance structures, incident response teams, and zero-trust architecture principles. Conduct regular risk assessments, vulnerability management, and penetration testing. Maintain security awareness programs with 95%+ staff completion and report KPIs quarterly. Develop and test business continuity and disaster recovery plans with defined RPO/RTO targets. AI Strategy & Implementation: Define organisational AI strategy and governance aligned with business objectives. Evaluate, pilot, and implement AI tools for operational efficiency and compliance. Establish ethical AI practices and risk management frameworks addressing bias, privacy, and regulatory concerns. Lead AI projects with measurable ROI and create staff competency development programs. Data Management & ICT Governance: Implement ICT governance frameworks (COBIT 2019, KING IV), ensuring compliance with POPIA, GDPR, and pharmaceutical regulations (GxP). Establish data governance standards, classification, and protection measures. Maintain audit readiness and manage vendor governance and third-party risk programs. Ensure timely preparation and submission of governance, strategic, and operational reports. Digital Transformation Oversight: Lead enterprise digital transformation initiatives aligned with organizational strategy. Manage ICT transformation projects using PMI or PRINCE2 methodologies. Drive automation, cloud migration, and digital workplace technologies. Oversee change management programs and ensure measurable business value delivery. Team Leadership & Project Management: Manage and develop IT teams, assign tasks, and conduct annual performance reviews. Lead IT projects from initiation to completion, ensuring delivery within scope, time, and budget. Foster team capabilities in emerging technologies, cybersecurity, and digital transformation. Budgeting, Procurement & Vendor Management: Prepare and manage annual IT budgets (CAPEX/OPEX) and monitor monthly expenses. Evaluate and select technology vendors, negotiate contracts, and manage service agreements. Ensure vendor solutions meet strategic objectives and compliance requirements. Technology Evaluation & Implementation: Assess emerging technologies (AI, automation, cybersecurity) for organizational impact. Secure stakeholder alignment and oversee successful change management during implementation.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources
Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.
Incomplete applications or applications without the aforementioned documents or information will not be considered.
No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal:https://www.sahpra.org.za/vacancies.
For enquiries: Please contact Mr I Mosenyi, HR Business Partner, via email at itumeleng.mosenyi@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 3 February 2026 at 16:00.
MANAGER: ICT
SALARY: R1 565 650 – R 1 661 741 PER ANNUM (TOTAL COST TO COMPANY)
Ref No.: SAHPRA 60 of 2025/26
CENTRE: Pretoria
REQUIREMENTS: ● Applicants must have a Matric certificate and an appropriate four-year Bachelors degree or equivalent NQF level 7 as recognised by the South African Qualifications Authority (SAQA) in Computer Science or an Information Technology related qualification.
Certification: COBIT 2019 Foundation, COBIT 2019 Design and Implementation certifications, ITIL Foundation and/or Practitioner certificate, CISSP (Certified Information Systems Security professional) or CISM (Certified Information Security Manager)
Other requirements: PMP (Project Management Professional) or PRINCE2 Practitioner, Cloud architecture certifications (AWS Solutions Architect, Azure Solutions Architect), AI/ML certifications (Microsoft AI Engineer, Google Cloud ML Engineer), Privacy certifications (CIPP/E, CIPM)
EXPERIENCE: Minimum of five (5) years progressive ICT management experience with a minimum of three years in senior leadership roles. ● Demonstrated experience in cybersecurity management and digital transformation leadership. ●Experience with AI/ML implementation and emerging technology adoption. ●Proven track record in regulatory compliance and governance (preferably pharmaceutical/healthcare)
COMPETENCIES, KNOWLEDGE AND SKILLS: *ICT Unit business leader & ICT Team leadership capabilities, *Advanced cybersecurity expertise including zero-trust architecture, SIEM/SOAR platforms, *AI/ML technologies, natural language processing, and intelligent automation, *Digital transformation methodologies and change management, *Digital transformation methodologies and change management, *Cloud computing architectures (hybrid, multi-cloud strategies), *Enterprise architecture frameworks (TOGAF, Zachman), *DevSecOps practices and infrastructure as code, *Solid Stakeholder management skills, *Solid Vendor management skills, *Effective Communication Skills, *Solid Leadership and Management Skills, *Performance measurement skills, *Performance measurement skills, *Problem-solving skills, *Budget Management skills, *ICT Unit business leader & ICT Team leadership capabilities,
DUTIES: Strategic Planning & Technology Leadership: Develop, secure approval, and implement strategic technology plans aligned with business goals and digital transformation objectives. Define and maintain enterprise architecture frameworks (e.g., TOGAF, Zachman) and technology roadmaps. Lead cloud migration strategies and implement Infrastructure as Code (IaC) solutions. Infrastructure & Application Management: Oversee IT infrastructure components, including servers, networks, storage systems, databases, and virtualization technologies. Ensure scalability, resilience, and security-by-design across all IT resources. Manage enterprise applications portfolio (ERP, CRM, regulatory systems), ensuring high availability (99.5%+) and optimal performance. Drive application lifecycle management, modernization initiatives, and cloud-first hosting strategies. Implement robust application security standards and manage integrations via API platforms. Cybersecurity & Risk Management: Develop and execute cybersecurity strategies aligned with ISO 27001 and NIST frameworks. Establish governance structures, incident response teams, and zero-trust architecture principles. Conduct regular risk assessments, vulnerability management, and penetration testing. Maintain security awareness programs with 95%+ staff completion and report KPIs quarterly. Develop and test business continuity and disaster recovery plans with defined RPO/RTO targets. AI Strategy & Implementation: Define organisational AI strategy and governance aligned with business objectives. Evaluate, pilot, and implement AI tools for operational efficiency and compliance. Establish ethical AI practices and risk management frameworks addressing bias, privacy, and regulatory concerns. Lead AI projects with measurable ROI and create staff competency development programs. Data Management & ICT Governance: Implement ICT governance frameworks (COBIT 2019, KING IV), ensuring compliance with POPIA, GDPR, and pharmaceutical regulations (GxP). Establish data governance standards, classification, and protection measures. Maintain audit readiness and manage vendor governance and third-party risk programs. Ensure timely preparation and submission of governance, strategic, and operational reports. Digital Transformation Oversight: Lead enterprise digital transformation initiatives aligned with organizational strategy. Manage ICT transformation projects using PMI or PRINCE2 methodologies. Drive automation, cloud migration, and digital workplace technologies. Oversee change management programs and ensure measurable business value delivery. Team Leadership & Project Management: Manage and develop IT teams, assign tasks, and conduct annual performance reviews. Lead IT projects from initiation to completion, ensuring delivery within scope, time, and budget. Foster team capabilities in emerging technologies, cybersecurity, and digital transformation. Budgeting, Procurement & Vendor Management: Prepare and manage annual IT budgets (CAPEX/OPEX) and monitor monthly expenses. Evaluate and select technology vendors, negotiate contracts, and manage service agreements. Ensure vendor solutions meet strategic objectives and compliance requirements. Technology Evaluation & Implementation: Assess emerging technologies (AI, automation, cybersecurity) for organizational impact. Secure stakeholder alignment and oversee successful change management during implementation.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources
Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.
Incomplete applications or applications without the aforementioned documents or information will not be considered.
No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal:https://www.sahpra.org.za/vacancies.
For enquiries: Please contact Mr I Mosenyi, HR Business Partner, via email at itumeleng.mosenyi@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 3 February 2026 at 16:00.
OFFICE MANAGER AND INTERNATIONAL RELATIONS IN THE OFFICE OF THE CHIEF EXECUTIVE OFFICER
Salary Level 13: R1 323 071 – R1 404 279 per annum (TOTAL COST TO COMPANY PACKAGE)
Ref No.: SAHPRA 59 of 2025/26
Centre: PRETORIA
REQUIREMENTS: A Matric certificate and a degree in Operations Management, Business or Public Management or Administration, or a relevant equivalent at NQF level 7 as recognised by the South African Qualifications Authority (SAQA). Management qualification (MBA/MBL/MAP) or Certificate in Project Management will be an added advantage.
EXPERIENCE: A minimum of 8 years’ experience in executive operations is required, including at least five years at a middle management or management level (Levels 11–13) supporting business operations. Proven experience in project management and stakeholder management is essential. Experience in the Company Secretariat will be advantageous. Knowledge of South African laws and health sector regulations will be an added advantage. Familiarity with government departments and public entities is important. A valid driver’s licence is also required, as the position involves travel.
REQUIRED KNOWLEDGE SKILLS, ABILITIES AND COMPETENCIES: Project Management, stakeholder liaison, and executive secretariat support. Governance and compliance expertise (PFMA, SAHPRA policies, SOPs, statutory reporting). Advanced MS Office Suite, financial oversight, and audit management. Strong communication, cross-functional coordination, and people leadership.
KEY DUTIES:
Operations: Develop and monitor the CEO office operational plans aligned to strategic goals, boosting productivity and efficiency. Oversee project execution from management and stakeholder meetings, preparing reports and resolutions. Advise the CEO on decisions, represent at meetings, manage communications, enquiries, and international partnerships. Coordinate cross-functional collaborations, workshops, and CEO interactions; provide secretariat support to committees. Support audits, risk 2 Advert: Office Manager in the Office of the Chief Executive Officer (CEO) committees, and executive meetings with follow-up reporting to the CEO. Liaise with the Communications team.
Governance & Compliance: Ensure accurate, timely statutory reporting and full adherence to SAHPRA policies, SOPs, ToRs, and manuals. Manage performance against standards, identifying innovative improvement opportunities.
Stakeholder Engagement: Build partnerships with public and private sectors to deliver SAHPRA programs sustainably. Execute stakeholder services per the Management Framework; share critical updates (e.g., strategy/legislative changes).
Financial Management: Oversee CEO committee claims processing, payments, and record-keeping; drive cost-saving initiatives per PFMA and Treasury rules.
People Management: Lead and develop CEO office team for high performance and efficiency.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
- Interested persons who meet the above-stated requirements should submit their application, clearly state the position name and post reference number, including a signed cover letter, clearly state the position name and post reference number, detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, copies of required qualifications (including matric) and Identity Document. ONLY shortlisted candidates will be required to submit certified copies of qualifications and other related documents on or before the day of the interview, following communication from Human Resources.
- Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from SAQA.
- Incomplete applications or applications without the aforementioned documents or information will not be considered.
- No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
- Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
- Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
- Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
- SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
- It is SAHPRA’s intention to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to are encouraged to apply and indicate their disability status.
- SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
- SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal: http://www.sahpra.org.za/vacancies
For enquiries: Please contact Ms Bafedile Rakgotho, HR Business Partner, via email at Bafedile.Rakgotho@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 30 January 2026 at 16:00.
MEDICINE REGISTRATION OFFICER: PHARMACOVIGILANCE (5 POSITIONS)
SALARY: R 738 611.00 – R 937 285.00 per annum (TOTAL COST TO COMPANY)
(Grade 1 – Grade 2) Market-related salary will be determined by the years of experience obtained post qualification, Internship and Community Service in line with governing frameworks.
Ref No.: SAHPRA 58 of 2025/26
CENTRE: PRETORIA
REQUIREMENTS: Matric certificate and appropriate four-year degree in Pharmacy at NQF Level 8 as recognised by the South African Qualifications Authority (SAQA) and registration with a Professional Body (South African Pharmacy Council). A relevant Masters degree will be an added advantage. A valid driver’s licence.
EXPERIENCE:
Grade 1 – A minimum of two (2) years of Pharmacovigilance experience post internship and Community Service. Regulatory experience will be an added advantage.
Grade 2 –A minimum of five (5) years of Pharmacovigilance experience post internship and Community Service.
COMPETENCIES, KNOWLEDGE, AND SKILLS:
DUTIES: Operational Management: Responsible for the accurate and timeous assessment of safety documents received, and performance as per the defined processes. Preparing comprehensive reports for various purposes (e.g., regulatory submissions, advisory committees, internal communication). Preparing accurate, timely, and well-documented reports that meet regulatory requirements. Documenting decision-making processes and justifications. Writing clear, concise, and evidence-based reports. Producing scientific peer-reviewed evaluation reports. Provide technical and administrative support to committees. Engaging stakeholders relating to regulatory matters. Manage product review systems. Processing applications received for approval.
Support the AEFI management: Conduct case management and causality assessments for AEFI cases for all registered vaccines. Establish integrated procedures and processes for monitoring, reporting, and assessment of vaccine-related safety concerns. Train healthcare professionals in the provinces on AEFI management, causality assessment, and AEFI reporting procedures and tools. Review, update, and implement updated procedures and processes for the management of registered vaccines.
Support Pharmacovigilance (PVC) and National Immunisation Safety Expert Committee (NISEC):
Support the PVC/NISEC both technically and administratively. Coordinate all PVC/NISEC meetings and minutes thereof. Allocate case files for clinical assessment to both pharmacovigilance technical officers and NISEC members. Update AEFI cases on the reports management system as per the NISEC causality assessment outcome. Prepare and provide monthly reports/statistics on AEFI cases. Ensure case closure and provision of feedback to the provinces. Prepare and communicate all regulatory decisions as per the meeting discussions.
Coordinate and support provinces on vaccines and therapeutics safety reporting and case management:
Support and strengthen linkages with provincial Departments of Health (DoH) to facilitate SAHPRA decentralised pharmacovigilance activities. Implement procedures and strengthen coordination with provincial and district-level DoH staff to improve AEFI and ADR reporting and case management activities. Develop/update reporting procedures for both AEFIs and therapeutics ADRs and coordinate finalisation. Strengthen provincial safety committees and linkages to SAHPRA.
Training and outreach: Coordinate and implement training for healthcare professionals in both private and private sectors. Coordinate medicine safety awareness webinars and workshops. Work closely with provinces and stakeholders for planning and implementation of outreach programmes for both healthcare professionals and the public. Benefit-Risk Evaluation: Critically assess Risk Management Plans (RMP)/Periodic Benefit-Risk Evaluation Reports (PBRER)/Periodic Safety Update Reports (PSUR)/Summary of Benefit-Risk Evaluation reports/Safety signals as submitted by applicants or received from any other stakeholder. Write clear, concise, and evidence-based reports. Produce scientific peer-reviewed reports for discussion. Timeous preparation and submission of assessment reports to ensure compliance with targets and timelines. Prepare and publish safety-related communications timeously.
ICSR Management: Processing and management of ADR/ADE reports received. Clinical assessment of serious adverse reaction reports. Coordinate and participate in causality assessment meetings of serious cases and cases of public interest. Conduct signal detection/assessment and necessary investigation.
Financial Management: Collating, compiling, and submitting accurate reports promptly to satisfy statutory and business requirements, as well as being able to communicate key financial messages to stakeholders with clarity and consistency. Provide general advice on all related financial matters to all relevant colleagues involved, directly or indirectly, in the financial circuit. Monitors and maintains all required financial records for compliance with all agreed requirements. Collate financial data and reports for analysis and to facilitate decision-making.
Governance, Compliance, and Risk: Achieve and maintain process quality. Adherence to the Occupational Health and Safety Act (OHSA) to ensure a safe and healthy working environment. Ensure adherence to all process quality assurance requirements. Assist with Performance Reporting within the predetermined timeline. Identify and record operational risks and consult with the Unit Manager. Mitigate risks within operational control. Resolve the operational risks effectively and timeously. Filing of evaluation reports under respective product folders. Assisting with the compliance of the Quality Management System requirements of the unit. Identify and record operational risks and consult with the Unit Manager. Development and maintenance of guiding principles (SOPs, guidelines, policies, etc.) to ensure consistency, efficiency, and alignment of PV processes. Identify and implement new approaches to improve and to maintain consistency, efficiency, and alignment of PV processes. Update policy documents to improve and maintain high levels of operational efficiency and effectiveness.
People Management: Self-management. Manage own Performance and Individual Development Plan. Living the SAHPRA values. Sharing knowledge with and informal coaching peers (as applicable).
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
Applications should be submitted through the SAHPRA Website Online Portal: https://www.sahpra.org.za/vacancies.
For enquiries: Please contact Ms Bafedile Rakgotho, HR Business Partner, via email at bafedile.rakgotho@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 30 January 2026 at 16:00.
MEDICINE REGISTRATION OFFICER: PHARMACOVIGILANCE (5 POSITIONS)
SALARY: R 738 611.00 – R 937 285.00 per annum (TOTAL COST TO COMPANY)
(Grade 1 – Grade 2) Market-related salary will be determined by the years of experience obtained post qualification, Internship and Community Service in line with governing frameworks.
Ref No.: SAHPRA 58 of 2025/26
CENTRE: PRETORIA
REQUIREMENTS: Matric certificate and appropriate four-year degree in Pharmacy at NQF Level 8 as recognised by the South African Qualifications Authority (SAQA) and registration with a Professional Body (South African Pharmacy Council). A relevant Masters degree will be an added advantage. A valid driver’s licence.
EXPERIENCE:
Grade 1 – A minimum of two (2) years of Pharmacovigilance experience post internship and Community Service. Regulatory experience will be an added advantage.
Grade 2 –A minimum of five (5) years of Pharmacovigilance experience post internship and Community Service.
COMPETENCIES, KNOWLEDGE, AND SKILLS:
- Knowledge and application of the Medicines and Related Substances Act, 101 of 1965, as amended, and its related regulations, with respect to the regulation of medicines in terms of quality, safety, and efficacy.
- Basic knowledge of the medicines regulatory framework, policies, and process.
- Knowledge and understanding of clinical pharmacology.
- Basic understanding of medicine registration and harmonisation.
- Excellent interpersonal and communication skills (written and verbal)
- Critical thinking
- Ability to exercise good judgment and solve problems quickly and effectively
- Computer skills
- Solution-oriented
- Ability to work under pressure
- Ability to maintain high levels of confidentiality
- Interpersonal skills
- Change management
- Knowledge management
- Service delivery innovation
- Problem-solving and analysis
- Client orientation and customer focus
- Proactive stakeholder management
- Situational adaptability
- Collaboration
DUTIES: Operational Management: Responsible for the accurate and timeous assessment of safety documents received, and performance as per the defined processes. Preparing comprehensive reports for various purposes (e.g., regulatory submissions, advisory committees, internal communication). Preparing accurate, timely, and well-documented reports that meet regulatory requirements. Documenting decision-making processes and justifications. Writing clear, concise, and evidence-based reports. Producing scientific peer-reviewed evaluation reports. Provide technical and administrative support to committees. Engaging stakeholders relating to regulatory matters. Manage product review systems. Processing applications received for approval.
Support the AEFI management: Conduct case management and causality assessments for AEFI cases for all registered vaccines. Establish integrated procedures and processes for monitoring, reporting, and assessment of vaccine-related safety concerns. Train healthcare professionals in the provinces on AEFI management, causality assessment, and AEFI reporting procedures and tools. Review, update, and implement updated procedures and processes for the management of registered vaccines.
Support Pharmacovigilance (PVC) and National Immunisation Safety Expert Committee (NISEC):
Support the PVC/NISEC both technically and administratively. Coordinate all PVC/NISEC meetings and minutes thereof. Allocate case files for clinical assessment to both pharmacovigilance technical officers and NISEC members. Update AEFI cases on the reports management system as per the NISEC causality assessment outcome. Prepare and provide monthly reports/statistics on AEFI cases. Ensure case closure and provision of feedback to the provinces. Prepare and communicate all regulatory decisions as per the meeting discussions.
Coordinate and support provinces on vaccines and therapeutics safety reporting and case management:
Support and strengthen linkages with provincial Departments of Health (DoH) to facilitate SAHPRA decentralised pharmacovigilance activities. Implement procedures and strengthen coordination with provincial and district-level DoH staff to improve AEFI and ADR reporting and case management activities. Develop/update reporting procedures for both AEFIs and therapeutics ADRs and coordinate finalisation. Strengthen provincial safety committees and linkages to SAHPRA.
Training and outreach: Coordinate and implement training for healthcare professionals in both private and private sectors. Coordinate medicine safety awareness webinars and workshops. Work closely with provinces and stakeholders for planning and implementation of outreach programmes for both healthcare professionals and the public. Benefit-Risk Evaluation: Critically assess Risk Management Plans (RMP)/Periodic Benefit-Risk Evaluation Reports (PBRER)/Periodic Safety Update Reports (PSUR)/Summary of Benefit-Risk Evaluation reports/Safety signals as submitted by applicants or received from any other stakeholder. Write clear, concise, and evidence-based reports. Produce scientific peer-reviewed reports for discussion. Timeous preparation and submission of assessment reports to ensure compliance with targets and timelines. Prepare and publish safety-related communications timeously.
ICSR Management: Processing and management of ADR/ADE reports received. Clinical assessment of serious adverse reaction reports. Coordinate and participate in causality assessment meetings of serious cases and cases of public interest. Conduct signal detection/assessment and necessary investigation.
Financial Management: Collating, compiling, and submitting accurate reports promptly to satisfy statutory and business requirements, as well as being able to communicate key financial messages to stakeholders with clarity and consistency. Provide general advice on all related financial matters to all relevant colleagues involved, directly or indirectly, in the financial circuit. Monitors and maintains all required financial records for compliance with all agreed requirements. Collate financial data and reports for analysis and to facilitate decision-making.
Governance, Compliance, and Risk: Achieve and maintain process quality. Adherence to the Occupational Health and Safety Act (OHSA) to ensure a safe and healthy working environment. Ensure adherence to all process quality assurance requirements. Assist with Performance Reporting within the predetermined timeline. Identify and record operational risks and consult with the Unit Manager. Mitigate risks within operational control. Resolve the operational risks effectively and timeously. Filing of evaluation reports under respective product folders. Assisting with the compliance of the Quality Management System requirements of the unit. Identify and record operational risks and consult with the Unit Manager. Development and maintenance of guiding principles (SOPs, guidelines, policies, etc.) to ensure consistency, efficiency, and alignment of PV processes. Identify and implement new approaches to improve and to maintain consistency, efficiency, and alignment of PV processes. Update policy documents to improve and maintain high levels of operational efficiency and effectiveness.
People Management: Self-management. Manage own Performance and Individual Development Plan. Living the SAHPRA values. Sharing knowledge with and informal coaching peers (as applicable).
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
- Interested persons who meet the above-stated requirements should submit their application, including a signed cover letter. Clearly state the position name and post reference number, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, copies of required qualifications (including matric), and an Identity Document. ONLY shortlisted candidates will be required to submit certified copies of qualifications and other related documents on or before the day of the interview, following communication from Human Resources.
- Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from SAQA.
- Incomplete applications or applications without the aforementioned documents or information will not be considered.
- No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
- Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application to be unsuccessful.
- Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
- Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
- SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
- SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
- SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
- SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal: https://www.sahpra.org.za/vacancies.
For enquiries: Please contact Ms Bafedile Rakgotho, HR Business Partner, via email at bafedile.rakgotho@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 30 January 2026 at 16:00.
RADIATION INSPECTOR
(FIXED TERM CONTRACT: UNTIL 31 MARCH 2028)
SALARY: R 935 152.00 – R 992 542.00 per annum (TOTAL COST TO COMPANY)
Ref No.: SAHPRA 54 of 2025/26
CENTRE: Durban
REQUIREMENTS: ● Matric certificate plus a BSc Hons Medical Physics * Professional registration with HPCSA * Valid driver’s licence is essential.
EXPERIENCE: ● Minimum experience of five years working as a Medical Physicist in Radiation Oncology, and/or Nuclear Medicine, and/or Diagnostic Radiology. Working knowledge of and experience with relevant national legislation and international standards.
COMPETENCIES, KNOWLEDGE AND SKILLS
Comprehensive knowledge and understanding of relevant legislation, protocols, standard operating procedures, and work instructions. Self-motivated with the ability to work independently. Proven ability to manage and collaborate with cross-functional teams. Strong problem-solving, research, and team-building skills, with a high level of attention to detail. Demonstrated capability in information evaluation, sound decision-making, and objective judgment. Resilient, assertive, and committed to ethical conduct and customer service excellence. Excellent communication skills (verbal, written, negotiation, conflict management, and presentation), supported by strong interpersonal abilities. Effective planning, organising, and team management skills. Proficient in MS Office.
DUTIES: ● Operations and processes of the sub-unit: Plan and perform inspections in accordance with the Hazardous Substances Act, related regulations and code of practice * Ensure enforcement of related regulations to non-compliant licence holders * Prepare formal reports of your finding/s during inspections * Attend to queries related to radiation control inspectorate sub-unit * Assist in ensuring accuracy and improvement of the database of the subunit.
● Performing inspections: Participate in inspection activities involving high-risk electronic generators of ionising radiation, such as linear accelerators, cyclotrons, industrial radiography etc * Perform radiation safety measurements to ensure regulatory compliance of licence holders in accordance with national regulations and codes of practice * Verification of quality control tests from licence holders’ equipment as prescribed by national standards.
● Management of incident reporting procedures: Receive and investigate incidents and accidents as reported by licence holders * Receive and investigate occupational radiation overexposures from licence holders as supplied by approved dosimetry laboratories * Provide analyses and reports in accordance with standard procedures and prescribed format * Ensure international standards are maintained in managing the radiation protection processes.
●Management of risks and audit queries: Developing and implementing of guidelines, code of conducts and standard operating procedures * Participate in offering advises and training/workshop to industry stakeholders related to the subunit * Participate in national and/or international collaboration related to regulatory function under the guidance of Deputy Manager, Assistant Manager and Senior Management * Receive and respond to various queries received by the subunit in accordance with query management standard procedure.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
Applications should be submitted through the SAHPRA Website Online Portal: http://www.sahpra.org.za/vacancies
For enquiries: Please contact Mr T Khunou, HR Business Partner, via email at Tshepo.Khunou@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 29 January 2026 at 16:00.
RADIATION INSPECTOR
(FIXED TERM CONTRACT: UNTIL 31 MARCH 2028)
SALARY: R 935 152.00 – R 992 542.00 per annum (TOTAL COST TO COMPANY)
Ref No.: SAHPRA 54 of 2025/26
CENTRE: Durban
REQUIREMENTS: ● Matric certificate plus a BSc Hons Medical Physics * Professional registration with HPCSA * Valid driver’s licence is essential.
EXPERIENCE: ● Minimum experience of five years working as a Medical Physicist in Radiation Oncology, and/or Nuclear Medicine, and/or Diagnostic Radiology. Working knowledge of and experience with relevant national legislation and international standards.
COMPETENCIES, KNOWLEDGE AND SKILLS
Comprehensive knowledge and understanding of relevant legislation, protocols, standard operating procedures, and work instructions. Self-motivated with the ability to work independently. Proven ability to manage and collaborate with cross-functional teams. Strong problem-solving, research, and team-building skills, with a high level of attention to detail. Demonstrated capability in information evaluation, sound decision-making, and objective judgment. Resilient, assertive, and committed to ethical conduct and customer service excellence. Excellent communication skills (verbal, written, negotiation, conflict management, and presentation), supported by strong interpersonal abilities. Effective planning, organising, and team management skills. Proficient in MS Office.
DUTIES: ● Operations and processes of the sub-unit: Plan and perform inspections in accordance with the Hazardous Substances Act, related regulations and code of practice * Ensure enforcement of related regulations to non-compliant licence holders * Prepare formal reports of your finding/s during inspections * Attend to queries related to radiation control inspectorate sub-unit * Assist in ensuring accuracy and improvement of the database of the subunit.
● Performing inspections: Participate in inspection activities involving high-risk electronic generators of ionising radiation, such as linear accelerators, cyclotrons, industrial radiography etc * Perform radiation safety measurements to ensure regulatory compliance of licence holders in accordance with national regulations and codes of practice * Verification of quality control tests from licence holders’ equipment as prescribed by national standards.
● Management of incident reporting procedures: Receive and investigate incidents and accidents as reported by licence holders * Receive and investigate occupational radiation overexposures from licence holders as supplied by approved dosimetry laboratories * Provide analyses and reports in accordance with standard procedures and prescribed format * Ensure international standards are maintained in managing the radiation protection processes.
●Management of risks and audit queries: Developing and implementing of guidelines, code of conducts and standard operating procedures * Participate in offering advises and training/workshop to industry stakeholders related to the subunit * Participate in national and/or international collaboration related to regulatory function under the guidance of Deputy Manager, Assistant Manager and Senior Management * Receive and respond to various queries received by the subunit in accordance with query management standard procedure.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
- Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources.
- Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.
- Incomplete applications or applications without the aforementioned documents or information will not be considered.
- No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
- Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
- Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
- Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
- SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
- SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be disabilities are encouraged to apply and indicate their disability status.
- SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
- SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal: http://www.sahpra.org.za/vacancies
For enquiries: Please contact Mr T Khunou, HR Business Partner, via email at Tshepo.Khunou@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 29 January 2026 at 16:00.
TECHNICAL OFFICER: MEDICAL DEVICES VIGILANCE (GRADE 1)
(FIXED-TERM CONTRACT POSITION UNTIL 31 MARCH 2028)
Ref No.: SAHPRA 56 of 2025/26
SALARY: R 738 611.00 – R783 939.00 per annum (TOTAL COST TO COMPANY)
CENTRE: Pretoria
REQUIREMENTS: Matric certificate and four-year degree in Pharmacy or Honours degree in Natural/Medical Sciences/Clinical Engineering at NQF level 8 as recognised by the South African Qualifications Authority (SAQA). Registration with the relevant professional body.
EXPERIENCE: Minimum three (3) years’ experience, of which two (2) years must be regulatory in Medical Devices and IVDs. Knowledge and/or understanding of Medical Devices Licensing, Vigilance, and Post Marketing Surveillance requirements.
CORE COMPETENCIES, TECHNICAL PROFICIENCIES, AND VALUES: Comprehensive knowledge and understanding of relevant legislation, the Medicine and Related Substances Act 101 of 1965 (as amended), Regulations relating to Medical Devices and IVDs. Computer literacy and MS Windows computer skills, Excel, and database applications. Good report writing and presentation skills. Good planning and organisational skills. Good verbal and written communication skills. Self-motivated and able to work independently. Ability to manage a variety of cross-functional team members. Pay attention to detail and information evaluation. Ethical behaviour and adherence to the SAHPRA Code of Conduct. At SAHPRA, we adhere to our core values: ubuntu, responsiveness, integrity, transparency, efficiency, collaboration, and excellence.
DUTIES: Perform risk-based evaluation of vigilance reports for medical devices and IVDs. Manage further handling of vigilance activities and maintain relevant databases. Develop and maintain guidelines and standard operating procedures for Medical Devices Licensing and Vigilance. Evaluate and manage licensing activities and applications for medical device establishments and maintain relevant databases. Prepare reports for SAHPRA and relevant advisory committees. Assist in minuting the recommendations of relevant advisory committees of SAHPRA applicable to the activities of the unit. Liaise with international regulatory authorities. Communicate with the relevant stakeholders and authorities from industry regarding the SAHPRA Board resolutions, legislative requirements for medical devices, and IVDs. Investigate and attend to industry/applicants’ queries. Capture and maintain data relating to measuring and monitoring performance metrics and peer-reviewed reports, and record statistics generated. Manage the associated risks, audit queries, and correspondence from applicants and stakeholders. Submit a weekly work plan and output to the Unit Manager (quantitative and qualitative reports). Perform other related functions that may arise from time to time.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
Applications should be submitted through the SAHPRA Website Online Portal: https://www.sahpra.org.za/vacancies.
For enquiries: Please contact Mr T Khunou, HR Business Partner, via email at Tshepo.Khunou@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 29 January 2026 at 16:00.
TECHNICAL OFFICER: MEDICAL DEVICES VIGILANCE (GRADE 1)
(FIXED-TERM CONTRACT POSITION UNTIL 31 MARCH 2028)
Ref No.: SAHPRA 56 of 2025/26
SALARY: R 738 611.00 – R783 939.00 per annum (TOTAL COST TO COMPANY)
CENTRE: Pretoria
REQUIREMENTS: Matric certificate and four-year degree in Pharmacy or Honours degree in Natural/Medical Sciences/Clinical Engineering at NQF level 8 as recognised by the South African Qualifications Authority (SAQA). Registration with the relevant professional body.
EXPERIENCE: Minimum three (3) years’ experience, of which two (2) years must be regulatory in Medical Devices and IVDs. Knowledge and/or understanding of Medical Devices Licensing, Vigilance, and Post Marketing Surveillance requirements.
CORE COMPETENCIES, TECHNICAL PROFICIENCIES, AND VALUES: Comprehensive knowledge and understanding of relevant legislation, the Medicine and Related Substances Act 101 of 1965 (as amended), Regulations relating to Medical Devices and IVDs. Computer literacy and MS Windows computer skills, Excel, and database applications. Good report writing and presentation skills. Good planning and organisational skills. Good verbal and written communication skills. Self-motivated and able to work independently. Ability to manage a variety of cross-functional team members. Pay attention to detail and information evaluation. Ethical behaviour and adherence to the SAHPRA Code of Conduct. At SAHPRA, we adhere to our core values: ubuntu, responsiveness, integrity, transparency, efficiency, collaboration, and excellence.
DUTIES: Perform risk-based evaluation of vigilance reports for medical devices and IVDs. Manage further handling of vigilance activities and maintain relevant databases. Develop and maintain guidelines and standard operating procedures for Medical Devices Licensing and Vigilance. Evaluate and manage licensing activities and applications for medical device establishments and maintain relevant databases. Prepare reports for SAHPRA and relevant advisory committees. Assist in minuting the recommendations of relevant advisory committees of SAHPRA applicable to the activities of the unit. Liaise with international regulatory authorities. Communicate with the relevant stakeholders and authorities from industry regarding the SAHPRA Board resolutions, legislative requirements for medical devices, and IVDs. Investigate and attend to industry/applicants’ queries. Capture and maintain data relating to measuring and monitoring performance metrics and peer-reviewed reports, and record statistics generated. Manage the associated risks, audit queries, and correspondence from applicants and stakeholders. Submit a weekly work plan and output to the Unit Manager (quantitative and qualitative reports). Perform other related functions that may arise from time to time.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
- Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources
- Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from SAQA.
- Incomplete applications or applications without the aforementioned documents or information will not be considered.
- No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
- Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
- Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
- Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
- SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
- SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
- SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
- SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your purposes.
Applications should be submitted through the SAHPRA Website Online Portal: https://www.sahpra.org.za/vacancies.
For enquiries: Please contact Mr T Khunou, HR Business Partner, via email at Tshepo.Khunou@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 29 January 2026 at 16:00.
ADMIN SCREENER: RADIATION CONTROL (X-RAY LICENSING)
SALARY: R 309 253.00 – R 328 223.00 per annum (TOTAL COST TO COMPANY)
Ref No.: SAHPRA 57 of 2025/26
CENTRE: Cape Town
REQUIREMENTS: ● Matriculation (NQF Level 4) *Post matric certification/Diploma with 1 to 2 years of experience in MS Office (Excel and Word), email/Outlook, office administration, and filing *Basic radiation control knowledge will be an added advantage.
COMPETENCIES, KNOWLEDGE AND SKILLS:
Demonstrating thorough knowledge and understanding of sound administrative and reporting requirements. Maintaining a high level of accuracy in preparing and entering information and demonstrating strong attention to detail. Writing clear, comprehensive reports. Displaying excellent interpersonal, written, and verbal communication skills. Thinking critically and exercising good judgment to solve problems quickly and effectively. Utilizing computer skills proficiently. Managing time efficiently. Solving problems resourcefully. Focusing on client orientation and customer service. Maintaining high levels of confidentiality. Demonstrating professionalism, honesty, and integrity. Keeping accurate records.
DUTIES: Screening Administrative Support:
• Uploads applications and related documentation, in accordance with standard operating procedures.
• Receives and log electronic applications from industry.
• Captures relevant details into the database as per SOP.
• Screens applications using a screening checklist and noting omissions.
• Sends incomplete or incorrect application forms back to the applicant for correction
• Assesses application against the relevant electronic administrative checklist.
• Submits administrative queries resulting from screening and applicants to the relevant manager.
• Sends screened license applications to the technical reviewer to finalise the screening before sending for licensing.
Administrative Support and Compliance:
• Ensures the business unit complies with the approved Standard Operating Procedures.
• Manages and updates the electronic data storage system.
• Manage communication from the unit manager and follow up on given tasks.
• Manage travel and accommodation arrangements for the unit.
• Manage scheduling of unit meetings and workshops.
Follow up of outstanding information and inspection report responses:
• Follow-up of outstanding info on received application forms within 5 working days.
• No response - telephone call.
• No response within 5 working days - discuss plan of action with Assistant Manager or Deputy Manager.
• Once inspection reports are sent by email by the inspector to the licence holder.
• Pend 30 days from the date the report was sent by email.
• Send reminders via email within 3 days of the pending date.
Management of risk and audit queries:
• Admin: Confirmation of inspection dates, timeous sending of inspection reports. and issuing pending files to the inspector for follow-up, ensuring completion of filing tasks – files are kept up to date.
• Ensure that the document management system is up to date.
• Assets: Manage office equipment and consumables.
• Effective handling of enquiries from the public and licence holders and admin tasks related to the queries.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
- Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources
- Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.
- Incomplete applications or applications without the aforementioned documents or information will not be considered.
- No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
- Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
- Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
- Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
- SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
- SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
- SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
- SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal: http://www.sahpra.org.za/vacancies
For enquiries: Please contact Mr T Khunou, HR Business Partner, via email at Tshepo.Khunou@sahpra.org.za.
NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 29 January 2026 at 16:00.
MEDICINES REGISTRATION OFFICER: PRE-REGISTRATION (GRADE 1)
(PHARMACEUTICAL EVALUATION MANAGEMENT)
(CONTRACT POSITION UNTIL 31 MARCH 2028)
SALARY: R738 611.00 – R783 939.00 per annum (TOTAL COST TO COMPANY)
REF NO.: SAHPRA 55 of 2025/26
CENTRE: Pretoria
REQUIREMENTS: ● Applicants must have a Matric certificate and an appropriate four-year Bachelor of Pharmacy degree and registration as a pharmacist with the South African Pharmacy Council (SAPC) at NQF Level 8 as recognised by the South African Qualifications Authority (SAQA) or an Honours degree in related health sciences at NQF Level 8 as recognised by SAQA. A relevant master’s qualification at NQF Level 9 as recognised by SAQA will be an added advantage. Valid driver’s licence required.
EXPERIENCE:
Grade 1: A minimum of three (3) years’ regulatory experience (post community service) in pharmaceutical or related medicines regulation or medicine production quality assurance; OR an Honours degree in related health sciences at NQF Level 8 as recognised by SAQA plus a minimum of five (5) years’ regulatory experience in pharmaceutical or related medicines regulation or medicine production quality assurance.
COMPETENCIES, KNOWLEDGE AND SKILLS: *Knowledge and application of the Medicines and Related Substances Act, 101 of 1965, as amended, and its related Regulations and guidelines. *Knowledge of the technical aspects for the evaluation of the quality and efficacy (bioequivalence) of medicines. *Computer literacy and a sound working knowledge of computer software packages. *Technical and scientific aspects of medicine regulation. *Evaluation guidelines as prescribed by the relevant regulatory authorities. *Planning and organisational skills. *Leadership skills. *Co-ordination skills. *Written and verbal communication skills. *Diversity management. *Time management. *Good telephone etiquette. *Supervisory skills.
DUTIES: ● Evaluation of new applications and peer reviewing of new applications: *Generate evaluation report(s) for each new application (new chemical entities (NCE) and Generics) in compliance with required template and adopted regulatory/scientific standards and submit for peer review. *Following the peer-review process, amend the report(s) accordingly to generate a list of queries to the applicant using the correct templates. *Peer review primary report(s) compiled by other reviewers. *Prepare reports for the internal working groups and, where necessary, present at the advisory committee for complex scientific matters. *Prepare query letters to applicants. *Prepare a basis of approval or rejection. *Provide quality assurance of reports and facilitate resolutions on technical matters.
● Evaluate applicant responses for registration/approval of medicines: *Generate second (and subsequent) evaluation reports for each response application and submit for peer-review in compliance with required template and adopted regulatory/scientific standards and submit for peer review. *Following the peer-review process, amend the report accordingly to generate a list of queries to the applicant, if necessary. *Peer review other evaluators’ response reports, according to the required template and adopted regulatory/scientific standards. *Prepare reports for the internal working groups and, where necessary, present at the advisory committee for complex scientific matters. *Prepare query letters to applicants. *Prepare a basis for approval or rejection. *Provide quality assurance of reports and facilitate resolutions on technical matters.
●Technical screening for the quality and efficacy (bioequivalence) aspects of new applications for the registration of medicines: *Generate technical screening evaluation reports for each application and submit for peer-review. *Following the peer-review process, amend the technical screening reports accordingly to generate a list of queries to the applicant using the correct templates. *Peer-review technical screening reports compiled by other reviewers. *Prepare screening query/screening rejection letters to applicants. *Provide quality assurance of reports and facilitate resolutions on technical matters.
● Develop and update guidelines, SOPs, and templates: *Review existing guidelines, standard operating procedures (SOPs), and templates and update when necessary. *Provide training on guidelines, SOPs, and templates. *Create new guidelines, SOPs, and templates where relevant. *Provide regular work plans and output to the unit manager (qualitative and quantitative reports). *Perform any other related duty as requested by the manager/senior manager.
● Form part of technical working groups or special projects and provide support to the unit as well as to advisory committees: *Participate in special projects and registration groups. *Lead and manage assessments, peer review, and discussion working groups, where relevant. *Compile discussion documents and reports. *Provide regular training to new internal medicine registration officers (MROs) and external evaluators. *Take comprehensive notes of discussions of relevant discussions. *Prepare documents for the SAHPRA management/RC meetings.
● Risk Management and Audit: *Adhere to SOPs and guidelines. *Create and maintain databases. *Use the most current templates and guidelines. *Provide and attend relevant training as may be necessary. *Align with Quality Management System requirements. *Align with the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use, World Health Organisation, International Pharmaceutical Regulators Programme, and other international standards.
INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):
- Interested persons who meet the above-stated requirements should submit their application, clearly state the position name and post reference number, including a signed cover letter, clearly state the position name and post reference number detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and copies of required qualifications (including matric). ONLY shortlisted candidates will be required to submit certified copies of qualifications and other related documents on or before the day of the interview, following communication from Human Resources.
- Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.
- Incomplete applications or applications without the aforementioned documents or information will not be considered.
- No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.
- Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.
- Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.
- Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.
- SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.
- SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.
- SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).
- SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013. CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.
Applications should be submitted through the SAHPRA Website Online Portal: http://www.sahpra.org.za/vacancies
For enquiries: Please contact Mr T Khunou, HR Business Partner, via email at Tshepo.Khunou@sahpra.org.za. NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.
The closing date is 29 January 2026 at 16:00.