SOUTH AFRICAN HEALTH PRODUCTS REGULATORY AUTHORITY (SAHPRA) VACANCIES - 07 MAY 2026

SOUTH AFRICAN HEALTH PRODUCTS REGULATORY AUTHORITY (SAHPRA)

The South African Health Products Regulatory Authority (SAHPRA) is the National Medicines Regulatory Authority established in terms of the Medicines and Related Substances Act, 101 of 1965, as amended, to monitor, evaluate , regulate , investigate , inspect, register and control medicines, schedule substances, clinical trials and medical devices, including IVDs, and related matters in the public interest.

SENIOR MANAGER: LABORATORY SERVICES

(FIXED TERM CONTRACT: FIVE (5) YEARS)

SALARY: R1 565 650.00 – R1 661 741.00 PER ANNUM (TOTAL COST TO COMPANY)

Ref No.: SAHPRA 04 of 2026/27

CENTRE: PRETORIA

REQUIREMENTS: Applicants must have a Matric certificate and an appropriate Master’s degree in Biochemistry, Biological Science or Biomedical Science. A relevant PhD degree will be an added advantage.

EXPERIENCE: Minimum of five (5) years proven managerial experience in a laboratory environment. Relevant experience of laboratory accreditation and Good Laboratory Practice (GLP). Professional registration is an added advantage.

Other requirements: Thorough knowledge of and experience in the small molecule (medicines) field; Thorough knowledge of Quality Management as well as experience in a quality-related area (i.e. Quality Assurance, Quality Control, Compliance); Thorough knowledge of applicable international and local guidelines and regulations (e.g. ISO/IEC 17025, GCP, GLP, GMP); In-depth knowledge of all the relevant guidance documents related to the testing and control and regulation of medicines, these include documents published by the NDoH, SAHPRA, WHO, EDQM, CHMP and ICH; In-depth knowledge of the manufacture of medicines; Knowledge of laboratory equipment operation and maintenance; Basic understanding of human resource management; Basic understanding of financial principles and management; Ability to lead and motivate functional groups to achieve objectives (i.e. groups with members from diverse backgrounds created to complete projects); Good communication skills and the ability to function in a multi-cultural setting; Fully computer literate (MS Word, Excel, Access and PowerPoint); Fully conversant in English (read, write and speak); Self-motivated with a willingness to accept responsibility and challenges; Analytical and problem solving; Driver’s license

TECHNICAL COMPETENCIES: Sound registration and laboratory knowledge of relevant legislation, requirements and procedures pertaining to small molecule medicine, vaccine knowledge is advantageous, Medicine and related substances act, Knowledge of the assessment of quality, safety and efficacy of medicines, Good Lab Practice, Good Manufacturing Practice, Ability to write scientific reports, Understanding of global harmonized GxP standards, Understanding PFMA requirements, Understanding of supply chain management processes for procurement.

GENERIC COMPETENCIES: Excellent interpersonal and communication skills (written and verbal), Critical thinking and the ability to exercise good judgment and solve problems quickly and effectively, Computer skills, Solution orientated, Work under pressure, Ability to maintain high Application of technologies, Budgeting and Finance Management, Continuous Improvement, Customer focused and Responsive, Managing Interpersonal Conflict and Resolving Problems, Networking and Building Bonds, Planning and Organising, Project Management, Team Leadership.

LEARDERSHIP COMPETENCIES: Strategic Leadership, People Management and Empowerment, Change Management, Knowledge Management, Service Delivery initiatives, Problem Solving and Analysis, Customer focused, Proactive Stakeholder Management

DUTIES: Strategic Management: Oversee the translation of strategic objectives into core operations plans. Scans external and internal environments to identify and assess emerging trends, opportunities and threats that may influence future directions. Define issues, generate options and select solutions, which are consistent with strategy and vision. Foresee obstacles and opportunities for the organization and act accordingly. Display and contribute in-depth knowledge to strategic planning at the organisational level. Ensure alignment of strategies across various functional areas to the organization strategy. Define performance measures to evaluate the success of organization’s strategy. Create new models and methods for improved service delivery by the organization. Develop contingency measures and explores various problem-solving options. Identify and evaluate the effectiveness and efficiency of the solutions after they have been implemented and identify changes needed; and develop contingency measures and explore various problem-solving options. Monitor and review strategic plans consistently and take corrective action to keep plans on track considering new challenges in the environment. Anticipate future knowledge management requirements and systems. Develop standards and processes to meet future knowledge management requirements.

Operational Management: Manage the operations of the unit with regards to the processes, inputs, targets, outputs and resourcing requirements to ensure effective operation within the unit. Offer technical advice and support to team members on a range of technical or laboratory-related issues or requirement. Apply knowledge of SAHPRA policies and procedures to identify and resolve complex issues and inconsistencies and make recommendations on initiatives, ensuring cohesive implementation of changes. Technical leads in the appeal processes for applicants that appeal the decisions of the organization. Manage the development of regulations, regulatory processes and guidelines within the relevant business unit to ensure efficiency, considering best practice and guidelines. Perform quality assurance of processes and outputs to ensure compliance with legislative and regulatory requirements. Application of scientific principles, regulatory requirements, best practices and quality assurance to team leader reviews for applications (If applicable). Perform team leader review and/or adjudicate peer-reviewed reports and provide technical decisions regarding applications. Review and ensure consistency in the applications. Responsible to capacitate various operations or work streams of the unit with the required adequately skilled staff and resources and to attain the mandate of the Unit. Allocates program or project resources in line with strategic direction. Identifies and prioritize resources across various initiatives or operations within the business unit. Development and continuous monitoring towards the implementation of the annual operational plan and business unit plans.

 Manage the various operations and processes of the relevant Business Unit in line with the relevant legal frameworks, prescribed local and international Guidelines.

 Continuous monitoring and effective compliant implementation of the business unit – specific AOP as per the approved plan:

o Monthly, quarterly, annual reporting on the progress of AOP/Business plan implementation

o Managing, developing, reviewing, and improving the accuracy of databases.

 Identify, participate, support, and coordinate research projects and new developments.

Stakeholder Management: Continuous, timely and effective management of both internal and external stakeholders using various methodology of engagement. Implementation of an identified stakeholder plan. Continuous engagement with relevant local, regional, continental and international stakeholders. Active participation (in leader role oractive member) in various stakeholder engagements as well as Engagement reports.

Financial Management: Develop or support the development of the programmes budget and management implementation thereto. Collaborate with Finance Business Unit to develop and manage the business unit’s annual budget. Ensure the effective implementation, management, monitoring of the business unit’s budget, and mitigate and report on any variances. Prepare and submit accurate financial reports within the required timeframe. Ensure revenue information is collated and provided to the Finance office within the required timeframe. Manage and ensure effective utilisation of resources to enhance value for money.

Governance, Risk and Compliance Management: Develop, review, update and implement policies related to Standard Operating Procedures and Guidelines. Adherence to Supply Chain Management and Public Finance Management Act aspects and other SAHPRA policies and procedures. Ensure process changes are processed through effective change control processes. Application of risk management in processes. Manage all relevant internal and external audits by responding swiftly to any non-conformances or audit findings that are raised and develop mitigation reports. Provide timely and accurate evidence and expert analysis to support the legal unit in addressing compliance issues and legal matters. Ensure deviations or non-conformances are recorded and responded to. Implementation of QMS Culture. Manage the development and continuous monitoring of the unit’s QMS – processes, guidelines in alignment with best practices (i.e., National, Regional, Continental, international). Manage the development and review of internal policies, in collaboration with senior management. Ensure compliance with implementation of approved processes. Ensure training records on all processes are maintained. Compile business unit quality reports as required for the business unit (monthly reports, internal reports, external reports). Identify business units’ risks, develop mitigation plans and oversee the implementation of mitigation plans. Ensuring readiness for internal and external audits by maintaining accurate records, documentation, and compliance with audit requirements.

People Management: Lead the Laboratory Management and Operational teams responsible for the adherence to the business units’ objectives (i.e., APP, AOP,. Build and drive a high-performance culture within the laboratory. Drive a culture of personal and professional development – continuous learning or good regulatory practices. Living up to the SAHPRA Values. Drive collaborative leadership. Implement a Performance Management system to improve and reward employee performance. Identify and developing high potential employees to build a talent pipeline to drive succession planning. Skills transfer. Proactive mentoring and coaching. Ensure that SAHPRA is an employer of choice by attracting and retaining high calibre employees who fit the organisational culture and drive the organisational values through effective people management programmes and initiatives. Create an environment that values employee engagement. Diversity and inclusion. Manage employee and labour relations, while promoting employee wellbeing and leading with empathy. Promoting employee wellbeing and leading with empathy. Project Management operations

INSTRUCTIONS TO APPLICANTS (HOW TO APPLY):

 Interested candidates who meet the above requirements should submit an application clearly indicating the title of the position and reference number. Applications must include a signed cover letter, a detailed Curriculum Vitae (CV) with the names and email addresses of three (3) referees, and certified copies of the required qualifications (including matric). Only shortlisted candidates will be required to submit certified copies of qualifications and other relevant documents on or before the interview date, as communicated by Human Resources

 Should you have a foreign qualification, your application must be accompanied by an evaluation certificate (report) from the SAQA.

 Incomplete applications or applications without the aforementioned documents or information will not be considered.

 No late applications will be accepted. Any submissions received after the specified date and time will not be considered, and CVs will not be returned.

 Due to the larger number of responses anticipated, communication will be limited to short-listed candidates only. Applicants who have not been contacted within three (3) months after the closing date should consider their application unsuccessful.

 Shortlisted candidates will be expected to attend selection interviews at a date, time, and location as specified by SAHPRA.

 Applicants should note that pre-suitability checks will be conducted after they have been shortlisted. Their appointment is subject to positive outcomes from these checks, which include security clearance, verification of qualifications, criminal records, credit checks, citizenship status, and work experience.

 SAHPRA is committed to being an equal opportunity employer. When filling vacant positions, the entity will consider the principles outlined in Section 195(1)(i) of the Constitution of the Republic of South Africa (1996) and the Employment Equity Act, 55 of 1998.

 SAHPRA intends to promote equity (race, gender, and disability) in line with the numeric targets in our Employment Equity plan. We are committed to this when recruiting internally and externally, with a policy to promote from within wherever possible. Preference will be given to suitably qualified individuals from previously disadvantaged groups. Applicants with disabilities are encouraged to apply and indicate their disability status.

 SAHPRA reserves the right not to make any appointment(s) to the advertised post(s).

 SAHPRA adheres to the provisions of the Protection of Personal Information Act (POPIA), 4 of 2013.

CVs will not be returned, as the personal information you provide will be used solely for recruitment purposes, specifically for the position or vacancy you have applied for. If your application is unsuccessful, your personal information will be retained for internal audit purposes.

 Applications should be submitted through the SAHPRA Website Online Portal: https://www.sahpra.org.za/vacancies.

 For enquiries: Please contact Mr I Mosenyi, HR Business Partner, via email at itumeleng.mosenyi@sahpra.org.za. NOTE: APPLICATIONS SUBMITTED TO THIS EMAIL ADDRESS WILL NOT BE CONSIDERED AS PART OF THE RECRUITMENT PROCESS.

 The closing date is 19 May 2026 at 16:00.

DESKTOP TECHNICIAN

SALARY: R458 454 – R486 591 PER ANNUM (TOTAL COST TO COMPANY)

Ref No.: SAHPRA 06 of 2026/27

CENTRE: PRETORIA

REQUIREMENTS: ● Applicants must have a Matric certificate and an appropriate three-year National Diploma or equivalent NQF level 6 as recognised by the South African Qualifications Authority (SAQA) in ICT related qualification.

Certification: CompTIA A+ Certification, CompTIA Network+ Certification, Microsoft Certified: Azure Administrator Associate or Microsoft Certified: Windows Server, Cisco Certified Network Associate (CCNA), Certified Information Systems Security Professional ITIL Foundation Certification as an added advantage.

EXPERIENCE: Minimum of three (3) years progressive ICT experience.

COMPETENCIES, KNOWLEDGE AND SKILLS: * ITIL (Information Technology Infrastructure Library): Understanding IT service management best practices and processes, ITSM (IT Service Management), Familiarity with service delivery, incident management, and problem resolution, Infrastructure Knowledge, A grasp of IT infrastructure components and systems, Technical Support, Ability to troubleshoot and resolve technical issues, Technical Proficiency, Networking Expertise:, Troubleshooting Skills, Security Knowledge, System Administration, Project Management, Documentation and Reporting, Customer Service Orientation, Adaptability and Learning Agility, Teamwork and Collaboration, Problem-Solving Attitude, Time Management, Mastery in configuring, installing, and maintaining hardware (servers, desktops, peripherals) and software (operating systems, applications, utilities), Strong understanding of network infrastructure (LAN/WAN, routers, switches, firewalls) and protocols (TCP/IP, DNS, DHCP), Ability to diagnose and resolve hardware, software, and network issues promptly and effectively, Knowledge of cybersecurity principles, practices, and tools to protect systems, networks, and data from breaches or attacks, Experience in administering servers (Windows/Linux), managing user accounts, permissions, and access rights. Skills to plan, execute, and oversee IT projects such as system upgrades, migrations, or deployments, Ability to maintain accurate records, document procedures, and prepare reports on IT operations and incidents, Strong interpersonal skills to provide technical support to end-users, resolve queries, and educate users on IT issues, Ability to stay updated with technological advancements, learn new technologies quickly, and adapt to changing IT environments, Capability to work effectively in a team environment, collaborate with colleagues, and mentor junior IT staff, Analytical mindset to identify root causes of IT problems and implement effective solutions, Efficiently prioritize tasks, manage workload, and meet deadlines in a dynamic IT environment, Leadership, People Management and Empowerment, Change Management, Knowledge Management, Service Delivery initiatives, Problem Solving and Analysis, Client Orientation and Customer focused, Proactive Stakeholder Management, Situational adaptability

DUTIES: Operational Management: Diagnose, troubleshoot and resolve all hardware incidents, Install and configure new IT equipment and peripherals and physically repair hardware that are out of warranty, Report on incidents and resolution rate, with potential recommendation on prevention of similar future incidents, Resolve 80% of all hardware related incidents within the SLA, Deploy, Configure and Troubleshoot business applications for Internal and External Stakeholders. Resolve incidents and upgrade different types of software, Resolve 80% of all software related incidents within the SLA. Governance, Risk and Compliance: Configure and troubleshoot issues with VPN and 3G mobile connections on users PC, Configure and troubleshoot LAN and WAN incidents on users’ PCs, Comply with all organizational requirements and standards in terms security and access, Follow appropriate procedures and regulatory requirements in terms of organizational and industry standards, Resolve 80% of all Network and security related incidents within the SLA Financial Management: Recommend and advise on viability and cost effectiveness of hardware and software, Technical assessment of hardware and software options in terms overall cost savings initiatives

People: Drive a high-performance culture within the ICT team, Drive a culture of personal and professional development, Living up to the SAHPRA Values, Drive collaborative leadership